Question

Motifs that can form α/β horseshoes conformation are rich with which protein residue?

(a) Proline

(b) Arginine

(c) Valine

(d) Leucine

The question was posed to me in quiz.

I need to ask this question from Protein Motifs and Domain Prediction topic in portion Sequence Alignment of Bioinformatics

Answer 1

Right answer is (d) Leucine

To elaborate: Specific pattern of Leucine residues, strands form a curved sheet with helices on the outside. Leucine-rich repeats (LRRs) are 20-29-residue sequence motifs present in a number of proteins with diverse functions. The primary function of these motifs appears to be to provide a versatile structural framework for the formation of protein-protein interactions.