Question

Which of the following wrongly describes protein domains?

(a) They are made up of one secondary structure

(b) Defined as independently foldable units

(c) They are stable structures as compared to motifs

(d) They are separated by linker regions

I have been asked this question in an interview.

Query is from Protein Motifs and Domain Prediction topic in section Sequence Alignment of Bioinformatics

Answer 1

Right choice is (a) They are made up of one secondary structure

To elaborate: Protein domains are made up of two or more motifs i.e. the secondary structure to form stable and folded 3-D structures. They are conserved part of the protein sequence and can evolve, function, and exist independently of the rest of the protein chain.