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Heat-shock response was first observed in which organism?

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Heat-shock response was first observed in which organism?

(a) C. elegans

(b) Drosophila

(c) Arabidopsis

(d) Bacteria

I had been asked this question during an online interview.

My enquiry is from Chemical Basis of Life topic in chapter Chemical Basis of Life of Cell Biology

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Correct choice is (b) Drosophila

For explanation: Heat shock response on the form of production of heat shock proteins was first observed in Drosophila. In 1962, an Italian biologist was studying the development of Drosophila when it was observed that increasing the temperature, at which larvae grow new heat shock proteins appear on the chromosome.

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