Question

Many studies have demonstrated that the distribution of similarity scores assumes a peculiar shape that resembles a highly skewed normal distribution with a long tail on one side. The distribution matches the _______

(a) Gumble elective value distribution

(b) Gumble extreme void distribution

(c) Gumble end value distribution

(d) Gumble extreme value distribution

I got this question in an interview for internship.

The doubt is from Statistical Significance of Sequence Alignment topic in portion Pairwise Sequence Alignment of Bioinformatics

Answer 1

Right answer is (d) Gumble extreme value distribution

To explain I would say: The mentioned Distribution pattern matches the Gumble extreme value distribution for which a mathematical expression is available. This means that, given a sequence similarity value, by using the mathematical formula for the extreme distribution, the statistical significance can be accurately estimated.