Question

Rigorously evaluating the performance of RNA prediction programs has traditionally been hindered by the dearth of three-dimensional structural information for RNA.

(a) True

(b) False

The question was asked at a job interview.

The question is from Performance Evaluation topic in section RNA Structure Prediction of Bioinformatics

Answer 1

The correct option is (a) True

Best explanation: The availability of recently solved crystal structures of the entire ribosome provides a wealth of structural details relating to diverse types of RNA molecules. The high resolution structural information can then be used as a benchmark for evaluating state-of-the-art RNA structure prediction programs in all categories.