Question

Chloroplast localization signals are also located in the __________ terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine.

(a) N, negatively

(b) C, negatively

(c) C, positively

(d) N, positively

I had been asked this question in a job interview.

This interesting question is from Protein Sorting topic in division Functional Genomics & Proteomics of Bioinformatics

Answer 1

Right option is (a) N, negatively

For explanation: Chloroplast localization signals are also called transit Peptides. An interesting feature of the proteins targeted for the chloroplasts is that the transit signals are bipartite.