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Which of the following is not one of the training sets in SignalP?

(a) Prokaryotes

(b) Eukaryotes

(c) Gram-positive bacteria

(d) Gram-negative bacteria

This question was posed to me in an interview for internship.

I would like to ask this question from Protein Sorting topic in chapter Functional Genomics & Proteomics of Bioinformatics

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Correct answer is (a) Prokaryotes

Explanation: This distinction is necessary because there are significant differences in the characteristics of the signal peptides from these organisms. Therefore, appropriate datasets need to be selected before analyzing the sequence. The program predicts both the signal peptides and the protease cleavage sites of the query sequence.

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