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Coregenes is a web-based program that determines a ________ set of genes based on comparison of ________ small genomes.

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Coregenes is a web-based program that determines a ________ set of genes based on comparison of ________ small genomes.

(a) vast, four

(b) core, fifteen

(c) core, four

(d) vast, fifteen

The question was posed to me by my college director while I was bunking the class.

This interesting question is from Comparative Genomics in section Genome Mapping, Assembly and Comparison of Bioinformatics

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Correct choice is (c) core, four

For explanation: The user supplies NCBI accession numbers for the genomes of interest. The program performs an iterative BLAST comparison to find orthologous genes by using one genome as a reference and another as a query. This pairwise comparison is performed for all four genomes. As a result, the common genes are compiled as a core set of genes from the genomes.

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