Question

Which of the following is untrue about Gene Order Comparison?

(a) When the order of a number of linked genes is conserved between genomes, it is called synteny

(b) Generally, gene order is much more conserved compared with gene sequences

(c) Generally, gene order is much less conserved compared with gene sequences

(d) It is in fact rarely observed among divergent species

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The above asked question is from Comparative Genomics topic in portion Genome Mapping, Assembly and Comparison of Bioinformatics

Answer 1

The correct choice is (b) Generally, gene order is much more conserved compared with gene sequences

Explanation: Gene order conservation is in fact rarely observed among divergent species. Therefore, comparison of syntenic relationships is normally carried out between relatively close lineages. However, if syntenic relationships for certain genes are indeed observed among divergent prokaryotes, they often provide important clues to functional relationships of the genes of interest.