Question

The translated sequence can then be compared to a database of protein sequences with the hope of finding a strong similarity to a protein of known function, and hence to identify the function of the cloned EST.

(a) True

(b) False

This question was posed to me by my college professor while I was bunking the class.

My enquiry is from Sequencing cDNA Libraries of Expressed Genes, Submission of Sequences to the Databases in section Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

The correct choice is (a) True

Easiest explanation: The translated sequence can then be compared in the mentioned way hence to identify the function of the cloned EST. The corresponding cDNA clone of the gene of interest can then be obtained and the gene completely sequenced.