Question

Which of the following is incorrect regarding First EF?

(a) It is a program that predicts promoters for bacterial DNA

(b) It is a web-based program that predicts promoters for human DNA

(c) It stands for First Exon Finder

(d) It integrates gene prediction with promoter prediction

This question was addressed to me in exam.

I'd like to ask this question from Prediction Algorithms in section Promoter and Regulatory Element Prediction of Bioinformatics

Answer 1

Right answer is (a) It is a program that predicts promoters for bacterial DNA

To elaborate: It uses quadratic discriminant functions (see Chapter 8) to calculate the probabilities of the first exon of a gene and its boundary sites. A segment of DNA (15 kb) upstream of the first exon is subsequently extracted for promoter prediction on the basis of scores for CpG islands.