Question

In a similar way to structure prediction methods models can be evaluated using RMSD to measure the similarity between two molecular complexes.

(a) True

(b) False

I had been asked this question in quiz.

My query is from Evaluation of Models & Visualization Methods topic in section Predicting the Structure of Protein – Biomolecular Interactions of Bioinformatics

Answer 1

The correct option is (a) True

Explanation: This is only the case if an experimental structure already exists. Several docking methods have been evaluated at ‘Critical Assessment of Structure Prediction 2’ (CASP2) for both protein-ligand and protein-protein interactions.