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Inactivation of which of the following leads to detachment of the apoptotic cell?

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Inactivation of which of the following leads to detachment of the apoptotic cell?

(a) FAK

(b) PKB

(c) PKC

(d) RAF1

I had been asked this question by my college director while I was bunking the class.

My question is from Cell Signaling and Signal Transduction topic in chapter Cell Signaling and Signal Transduction of Cell Biology

1 Answer

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Best answer
Right option is (a) FAK

Easy explanation: The focal adhesion kinase (FAK) is inactivated by the cleaving action of caspases during apoptosis. Cleavage of FAK leads to detachment of the apoptotic cell from its neighboring cells.

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