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Activation of P13K in adherent epithelial cell promotes ___________________

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Activation of P13K in adherent epithelial cell promotes ___________________

(a) glucose translocation

(b) cell survival

(c) cell transformation

(d) signal transduction

I had been asked this question in exam.

This intriguing question comes from Cell Signaling and Signal Transduction topic in division Cell Signaling and Signal Transduction of Cell Biology

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Correct choice is (b) cell survival

The best I can explain: P13K is an enzyme that gets activated by a wide range of stimuli. In adherent epithelial cells P13K promotes cell survival, while in an insulin-stimulated liver cell it promotes GLUT4 translocation and protein synthesis.

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