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Inactivation of which of the following leads to shrinkage of the nucleus?

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Inactivation of which of the following leads to shrinkage of the nucleus?

(a) lamin

(b) tubulin

(c) actin

(d) gelsolin

The question was posed to me by my school principal while I was bunking the class.

This interesting question is from Cell Signaling and Signal Transduction in section Cell Signaling and Signal Transduction of Cell Biology

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Right choice is (a) lamin

Easy explanation: Inactivation of lamins by the caspases leads to disassembly of nuclear lamina and shrinkage of the nucleus. Lamins are a special class of proteins that make up the inner lining of the nuclear envelope.

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