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The likelihood of having a child with Down syndrome increases with _________________

(a) age of father

(b) age of mother

(c) birth of siblings

(d) fertilization rate

The question was posed to me in an international level competition.

The above asked question is from Cellular Reproduction topic in chapter DNA Replication and Repair, Cellular Reproduction of Cell Biology

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Correct choice is (b) age of mother

For explanation: It is believed that the likelihood of having a child with Down syndrome increases with the age of mother – from 0.05% for mothers 19 years of age to greater than 3% for mothers of age 45.

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