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The SR proteins bind to the __________________

(a) Introns to be skipped

(b) Introns not to be skipped

(c) Exons to be skipped

(d) Exons not to be skipped

I got this question in unit test.

Question is taken from Post-Transcriptional Modification in division Gene Expression : Transcription Prokaryotes of Cytogenetics

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Correct option is (d) Exons not to be skipped

Best explanation: Binding of SR proteins on the exons ensure that the exon is not skipped. It doesn’t bind to intron and in some weak exons it helps in skipping the exon thus helping in alternate splicing.

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