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Homologous recombination can’t occur in which stage?

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Homologous recombination can’t occur in which stage?

(a) G2

(b) Bacterial fission

(c) G1

(d) S

I had been asked this question in exam.

The query is from Repair of DNA Damage: Recombinational and Bypass in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

1 Answer

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Right answer is (c) G1

The explanation is: For homologous recombination to take place there must be two sister chromatids with same or similar composition. This is available only after DNA replication, thus it can’t take place in G1 phase before replication.

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