Question

______________ inversions reduce crossing over in ______________

(a) Paracentric, Heterozygous

(b) Pericentric, Heterozygous

(c) Paracentric, homozygous

(d) Pericentric homozygous

The question was posed to me by my college professor while I was bunking the class.

The question is from Chromosomal Abnormality : Inversion topic in portion Chromosomal Basis of Inheritance of Cytogenetics

Answer 1

Correct option is (b) Pericentric, Heterozygous

Easiest explanation: In heterozygous female the pairing is due to looping and then recombination in pericentric region can produce abnormal chromosomes which don’t separate properly in anaphase. Thus, it prevents recombination in heterozygous females.