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Which of the following agents can lead to both addition and deletion mutation?

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Which of the following agents can lead to both addition and deletion mutation?

(a) UV

(b) 5 Bromo Uracil

(c) Proflavin

(d) Hydroxylation

I had been asked this question in examination.

This intriguing question comes from DNA Mutation topic in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

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The correct answer is (c) Proflavin

Explanation: Proflavin, like Ethidium bromide is an intercalating agent. This when inserted in DNA can lead to addition of a random base, and when lost can lead to deletion.

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