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DNA microsatellites are prone to which type of mutation?

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DNA microsatellites are prone to which type of mutation?

(a) Transition

(b) Transversion

(c) Addition

(d) Methylation

I got this question during an internship interview.

Origin of the question is Repair of DNA Damage: MMR, BER in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

1 Answer

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Best answer
Correct choice is (c) Addition

For explanation: DNA microsatellites have several repetitive sequences within it, thus these regions are prone to polymerase slippage that can lead to insertion or deletion of bases.

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