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Which of the following is not true about type II restriction endonuclease?

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Which of the following is not true about type II restriction endonuclease?

(a) Here Clevage and Methylation are by different enzymes

(b) In this case the recognition sequence is asymmetric

(c) It cleaves within the recognition sequence

(d) It can’t cleave at methylated sequences

The question was posed to me during a job interview.

The query is from Restriction Endonuclease in chapter Genomics : The Mapping and Sequencing of Genomes of Cytogenetics

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Right option is (b) In this case the recognition sequence is asymmetric

Easiest explanation: In case of recognition sequence type IIs the recognition site in asymmetric. While in case of type II the recognition site is symmetric.

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