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Which of the following will be seen to resolve the flap in eukaryotic short patch BER?

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Which of the following will be seen to resolve the flap in eukaryotic short patch BER?

(a) dRPases

(b) FEN1

(c) Pol Beta

(d) APE1

This question was addressed to me in homework.

My doubt is from Repair of DNA Damage: MMR, BER in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

1 Answer

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Best answer
Right answer is (c) Pol Beta

Explanation: In eukaryotes, there is no requirement of a phosphodiesterase to resolve the short flap generated by short patch BER. It is taken care of by pol beta.

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