Question

During _________________ both the H19 alleles are ___________________

(a) Oogenesis, inactivated

(b) Oogenesis, activated

(c) Oogenesis, hyper-activated

(d) Spermatogenesis, activated

This question was addressed to me by my school principal while I was bunking the class.

I need to ask this question from Silencing and Genomic Imprinting in section Regulating Gene Expression in Eukaryotes of Cytogenetics

Answer 1

Right option is (b) Oogenesis, activated

To explain: The genomic imprinting has to be reset in every generation. This is achieved via the means that the genes that are maternally inherited are activated during oogenesis and paternally inherited genes are inactivated during the same and reverse for spermatogenesis. H19 is maternally inherited.