Question

Which of the following is the correct characteristic of bio precursors/ metabolic precursors?

(a) The inert carrier is attached through a chemical bond

(b) There is no inert carrier

(c) There is a change in pH while the formulation

(d) The active drug is converted to its inert form chemically

I got this question in exam.

I'm obligated to ask this question of Prodrugs topic in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

Correct option is (d) The active drug is converted to its inert form chemically

Explanation: Bioprecursors/ metabolic precursors are obtained after chemical modification of the active drug. They are made to form inert molecules and thus they do not need a carrier. This moiety has the same lipophilicity as the parent drug.