Question

Single-dose bioavailability studies are simple and common.

(a) True

(b) False

The question was asked in an interview.

The doubt is from Bioavailability topic in portion Compartment Modelling, Non Linear Pharmacokinetics, Bioavailability and Bioequivalence of Drug Biotechnology

Answer 1

Correct choice is (a) True

The explanation is: Single-dose bioavailability studies are common, easy, offer less exposure to drugs and are less tedious. Although it is difficult in a single dose bioavailability study to predict the steady-state characteristics of a drug and inter-subject variability. Multiple dose study is difficult to control.