Question

Maternal drug metabolizing ability increases in the later stage of pregnancy.

(a) True

(b) False

This question was addressed to me by my school principal while I was bunking the class.

I'm obligated to ask this question of Drugs Biotransformation topic in section Biotransformation of Drugs of Drug Biotechnology

Answer 1

Right answer is (b) False

Easy explanation: Maternal drug metabolizing ability decreases in the later stage of pregnancy. Due to high levels of steroid hormones in circulation during pregnancy, in women, the metabolism of promazine and pethidine decreases. Thus, maternal drug metabolizing ability decreases.