Question

What are the names of the 3 protein involve in multienzyme mixed-function oxidase system, located in the endoplasmic reticulum?

(a) Heme protein, flavoprotein, phosphatidylcholine

(b) Heme protein, flavoprotein, retinal protein

(c) Heme protein, retinal protein, phosphatidylcholine

(d) Retinal protein, flavoprotein, phosphatidylcholine

The question was asked by my college director while I was bunking the class.

This interesting question is from Drugs Biotransformation topic in chapter Biotransformation of Drugs of Drug Biotechnology

Answer 1

Correct option is (a) Heme protein, flavoprotein, phosphatidylcholine

The best I can explain: Heme protein helps in oxidizing the substrate, flavoprotein functions as an electron carrier and catalyses the reduction of cytochrome 450 to ferrous form, phosphatidylcholine functions to facilitate electron transfer from NADPH to cytochrome 450.