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Which one of the following is the correct order of the drugs binding to various plasma protein?

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Which one of the following is the correct order of the drugs binding to various plasma protein?

(a) Albumin > alpha-1 acid glycoprotein > globulins  > lipoproteins

(b) Albumin > globulins  > lipoproteins > alpha-1 acid glycoprotein

(c) Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins

(d) Albumin > lipoproteins  > globulins  > alpha-1 acid glycoprotein

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Right option is (c) Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins

Explanation: The binding of the drug to the plasma protein is reversible. The extent of the binding is in the following order albumin > alpha-1 acid glycoprotein > lipoproteins > globulins. Drugs of all types, varieties can easily bind to the Human serum albumin.

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