Question

Drugs of molecular range 300-500 Dalton will be excreted out by glomerulus.

(a) True

(b) False

This question was posed to me in an international level competition.

Enquiry is from Drugs Excretion topic in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer 1

The correct answer is (b) False

For explanation: Compounds with molecular weight below 300 Dalton will be filtered easily through the glomerulus. Drugs in the molecular weight range of 300-500 Dalton will be filtered through the bile and urine both. Molecules of size more than 500 Dalton will be filtered out through urine but to a lesser extent.