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Which of the following fentanyl analogue is used in heart surgery?

(a) Alfentanyl

(b) Sufentanil

(c) Remifentanil

(d) Carfentanil

The question was asked during an online interview.

Question is taken from Opioid Analgesics topic in chapter Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

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Right option is (b) Sufentanil

The explanation is: Sufentanil, a potent analgesic, 5 to 10 times more potent than fentanyl for use in heart surgery. Alfentanil, ultra-short acting analgesic. Remifentanil, the shortest acting opioid, has the benefit of rapid offset, even after prolonged infusions. Carfentanil has analgesic potency 10,000 times that of morphine and is used in veterinary practice.

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