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Which of the following option will correct for the marked place?

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in Drug Biotechnology by (138k points)
Which of the following option will correct for the marked place?

(a) Urate crystal

(b) Interleukin-1

(c) Mononuclear phagocytes

(d) Prostaglandins

This question was addressed to me by my school principal while I was bunking the class.

Asked question is from Drug Addiction and Abuse in portion Local & General Anesthetics, Opioid Analgesics, Drug Addiction and Drug Abuse of Drug Biotechnology

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Best answer
Right choice is (c) Mononuclear phagocytes

Best explanation: Synoviocytes phagocytose urate crystals and then secrete inflammatory mediators. These inflammatory mediators attract and activate polymorphonuclear leukocytes and mononuclear phagocytes. Drugs active in gout inhibit crystal phagocytosis and polymorphonuclear leukocytes and macrophage release of inflammatory mediators such as prostaglandin, interleukin, and leukotriene.

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