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What is the site of action of the diuretic mannitol?

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What is the site of action of the diuretic mannitol?

(a) Proximal tubule

(b) Glomerulus

(c) Descending loop of Henle

(d) Distal Tubule

I have been asked this question in final exam.

My question is from Diuretics in section Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

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The correct option is (a) Proximal tubule

Explanation: Osmotic diuretics work in the proximal tubule, producing an osmotic effect. It pulls water into the blood vessels and nephrons from the surrounding tissues. Osmotic diuretics reduces cellular edema, increased urine production, causing diuresis. Rapid excretion of water, sodium, and other electrolytes, as well as excretion of toxic substances from the kidney. Reduced excessive intraocular pressure.

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