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Release of water-soluble drugs can be retarded by presenting it as ____________ suspension.

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Release of water-soluble drugs can be retarded by presenting it as ____________ suspension.

(a) Oil

(b) Water

(c) Colloidal

(d) Freezing

The question was asked during an interview.

This key question is from Biopharmaceuticals topic in portion Biopharmaceuticals of Drug Biotechnology

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Right answer is (a) Oil

Explanation: Release of water-soluble drugs can be retarded by presenting it as oil suspension. And oil-soluble drugs releasing can be retarded by presenting them in water suspension. The solid content should be in the range of 0.5 to 5.0%. Larger the particle size slower the dispersion since the surface area to volume ratio is less.

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