Question

Why human cells are more preferred for the production of the recombinant protein?

(a) Say in culturing

(b) More sterility

(c) Can be easily harvested

(d) Post-translational modification

The question was asked in an interview.

My doubt is from Genetic Recombination topic in chapter Genetic Recombination of Drug Biotechnology

Answer 1

Correct answer is (a) Say in culturing

To explain I would say: Mammalian cells most commonly used for gene delivery. More importantly Human cells- allows the production of recombinant protein with authentic post-translational modifications. Products which are made by gene transfer are antibodies, hormones, growth factors, cytokines, and vaccines.