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Which of these heat shock proteins prevent protein misfolding and maintain polypeptide chain in the unfolded state.

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Which of these heat shock proteins prevent protein misfolding and maintain polypeptide chain in the unfolded state.

(a) Hsp60

(b) Hsp28

(c) Hsp70

(d) Hsp32

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Enquiry is from Protein Folding in division Biomolecules and Catalysis of Life Sciences

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Correct option is (c) Hsp70

The explanation is: Hsp70 is induced by stress and these are the primary proteins which prevent polypeptide chain from misfolding and maintained it in an unfolded state. It also helps in translocation of the protein from the cytosol into ER or mitochondria.

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