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Oxygen affinity for hemoglobin is affected by Ph and this phenomenon is known as Bohr’s effect.

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Oxygen affinity for hemoglobin is affected by Ph and this phenomenon is known as Bohr’s effect.

(a) True

(b) False

The question was posed to me in a job interview.

The doubt is from Fibrous and Globular Proteins in section Biomolecules and Catalysis of Life Sciences

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Right option is (a) True

Explanation: PH has a strong effect on the oxygen affinity of hemoglobin. Lowering of Ph reduces the oxygen affinity of hemoglobin which shifts the sigmoidal curve to the right which and it shows that more partial pressure of oxygen is required for hemoglobin to bind the given amount of oxygen.

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