Question

The structures of this group of proteins, however, are comparatively a lot difficult to resolve either by x-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy.

(a) True

(b) False

The question was posed to me during an interview for a job.

My question is based upon Secondary Structure Prediction for Transmembrane Proteins in section Secondary Structure Prediction of Bioinformatics

Answer 1

Correct choice is (a) True

Best explanation: For this group of proteins, prediction of the transmembrane secondary structural elements and their organization is particularly important. Fortunately, the prediction process is somewhat easier because of the hydrophobic environment of the lipid bilayers, which restricts the transmembrane segments to be hydrophobic as well.