Question

Which of the following transfers malonyl group from co-A to ACP?

(a) Acyl carrier protein

(b) Acetyl co-A ACP transacetylase

(c) Enoyl-ACP reductase

(d) Malonyl co-A ACP transferase

This question was posed to me by my college professor while I was bunking the class.

Asked question is from Biosynthesis of Fatty Acids and Eicosanoids topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer 1

Right choice is (d) Malonyl co-A ACP transferase

For explanation I would say: Acyl carrier protein carries acyl groups in thio-ester linkage.

Acetyl co-A ACP transacetylase transfers acyl group from co-A to cys residue of KS.

β-ketoacyl ACP synthase condenses acyl and malonyl groups.