Question

Which of the following carries acyl groups in thio-ester linkage?

(a) Acyl carrier protein

(b) Acetyl co-A ACP transacetylase

(c) Enoyl-ACP reductase

(d) Malonyl co-A ACP transferase

This question was addressed to me during an online interview.

I want to ask this question from Biosynthesis of Fatty Acids and Eicosanoids topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer 1

Right choice is (a) Acyl carrier protein

For explanation: Acetyl co-A ACP transacetylase transfers acyl group from co-A to cys residue of KS.

β-ketoacyl ACP synthase condenses acyl and malonyl groups.

Malonyl co-A ACP transferase transfers malonyl group from co-A to ACP.