Question

Which of the following reduces β-keto group to β-hydroxyl group?

(a) β-ketoacyl ACP reductase

(b) β-hydroxyacyl ACP dehydratase

(c) Enoyl ACP reductase

(d) Malonyl co-A ACP transferase

I have been asked this question during an online exam.

Query is from Biosynthesis of Fatty Acids and Eicosanoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer 1

Right choice is (a) β-ketoacyl ACP reductase

To elaborate: β-hydroxyacyl ACP dehydratase removes H2O from β-hydroxyl ACP, creating double bond.

Enoyl ACP reductase reduces double bond, forming saturated acyl ACP.

Malonyl co-A ACP transferase transfers malonyl group from co-A to ACP.