Question

Which of the following removes H2O from β-hydroxyl ACP, creating double bond?

(a) β-ketoacyl ACP reductase

(b) β-hydroxyacyl ACP dehydratase

(c) Enoyl ACP reductase

(d) Malonyl co-A ACP transferase

The question was asked by my college director while I was bunking the class.

My question is based upon Biosynthesis of Fatty Acids and Eicosanoids in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer 1

The correct choice is (b) β-hydroxyacyl ACP dehydratase

For explanation: Enoyl ACP reductase reduces double bond, forming saturated acyl ACP.

Malonyl co-A ACP transferase transfers malonyl group from co-A to ACP.

β-Ketoacyl ACP reductase reduces β-keto group to β-hydroxyl group.