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At present, there are essentially two types of method of RNA structure prediction. One is the minimum free energy approach and the Second one is a comparative approach.

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At present, there are essentially two types of method of RNA structure prediction. One is the minimum free energy approach and the Second one is a comparative approach.

(a) True

(b) False

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Query is from RNA Secondary Structure Prediction Methods topic in portion RNA Structure Prediction of Bioinformatics

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Correct option is (a) True

The explanation: One is based on the calculation of the minimum free energy of the stable structure derived from a single RNA sequence. This can be considered an ab initio approach. The second is a comparative approach which infers structures based on an evolutionary comparison of multiple related RNA sequences.

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