Question

The ILM program uses an iterative loop matching algorithm to maximize base pairs and allows pseudoknots to form by allowing base. pairs to be added or removed in successive rounds.

(a) True

(b) False

I had been asked this question in an internship interview.

This interesting question is from Searching Genomes for RNA & RNA Structure Modeling Applications in portion RNA Structure Prediction of Bioinformatics

Answer 1

Correct option is (a) True

To explain I would say: The Nussinov algorithm, or maximum loop matching algorithm, is the basic framework for generating a structure with the most possible base pairs. The base pairs are ranked using both thermodynamic parameters and covariation data for aligned sequences. ILM requires the RnaViz program to visualize the RNA secondary structure with pseudoknots.