Question

The probabilistic model was used to identify small nucleolar (sno) RNAs in the yeast genome that methylate ribosomal RNA.

(a) True

(b) False

I had been asked this question in unit test.

The question is from Searching Genomes for RNA & RNA Structure Modeling Applications topic in portion RNA Structure Prediction of Bioinformatics

Answer 1

Correct choice is (a) True

The explanation is: The model is not used to search genomic sequences directly. Instead, a list of candidate sequences is first found by searching for patterns that match the sequences in the model (Lowe and Eddy 1999).