Question

Which of the given statement is incorrect about Functional Genomics?

(a) Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene

(b) An abnormal properties of the mutant organism does not reveal the gene function

(c) When two or more members of a gene family are found, rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family

(d) A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection

I got this question in homework.

My question is from Sequence Assembly and Gene Identification in section Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

The correct answer is (b) An abnormal properties of the mutant organism does not reveal the gene function

Easy explanation: The gene function is revealed by any abnormal properties of the mutant organism. This methodology provides a way to test a gene function that is predicted by sequence similarity to be the same as that of a gene of known function in another organism. If the other organism is very different biologically (comparing a predicted plant or animal gene to a known yeast gene), then functional genomics can also shed light on any newly acquired biological role.