Question

Which of the given statement is incorrect about the gene map?

(a) Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by reassembly of fragments in a different order can produce new gene maps

(b) Gene order is only revealed by the physical order of genes on the chromosome

(c) Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next

(d) These types of evolutionary changes in genomes have been modeled by computational methods

The question was posed to me during an interview.

I need to ask this question from Sequence Assembly and Gene Identification topic in section Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

Correct answer is (b) Gene order is only revealed by the physical order of genes on the chromosome

Explanation: Gene order is revealed not only by the physical order of genes on the chromosome but also by genetic analysis. Populations of an organism show sequence variations that are readily detected by DNA sequencing and other analysis methods. The inheritance of genetic diseases in humans and animals (e.g., cancer and heart disease), and of desirable traits in plants, can be traced genetically by pedigree analysis or genetic crosses.