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Which of the following is used to lyse the nucleus and release the DNA?

(a) sodium dodecyl sulfate

(b) ammonium sulfate

(c) ferric phosphate

(d) fluorine

The question was posed to me by my school principal while I was bunking the class.

Question is from Nucleic-acid Techniques in division Techniques in Cell Biology of Cell Biology

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Correct option is (a) sodium dodecyl sulfate

Easiest explanation: Sodium dodecyl sulfate (SDS) is an anionic detergent used to lyse the nucleus and release their nuclear content. Release of DNA also increases the viscosity of the solution and SDS inhibits nuclease activity in the solution.

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