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What is the range of telomere suppression?

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What is the range of telomere suppression?

(a) 1kb

(b) 3kb

(c) 4kb

(d) 10kb

I got this question during an online interview.

My question is based upon Transcription in Eukaryotes : Gene Silencing at Telomere topic in section Gene Expression : Transcription Prokaryotes of Cytogenetics

1 Answer

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Correct answer is (c) 4kb

Explanation: The telomere suppression spreads up to 4kb from the telomere. This is possible due to the looping action of RPA1 and SIR2-4 proteins by protein-protein interactions. The history at this regions are hemi-acetylated.

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