Question

Which of the following is not a point mutation?

(a) Substitution

(b) Transposition

(c) Insertion

(d) Transversion

The question was asked in an interview for job.

The doubt is from DNA Mutation in section DNA Mutation, DNA Repair, Transposable Elements of Cytogenetics

Answer 1

Correct choice is (b) Transposition

Explanation: Point mutation concerns a single base. Thus substitution, which includes transversion, and insertion or deletion, falls within point mutation. On the other hand, translocation involves a stretch of bases so it is not a point mutation.